The effects of cyclizine on the fetus
Cyclizine is a medicine that is used to treat and prevent nausea and vomiting. It is also used to treat and prevent vertigo (dizziness). It is not known if cyclizine passes into breast milk. If it does, it may cause side effects in a child who is breastfed. You should not breastfeed while you are taking cyclizine. Cyclizine may cause side effects. Tell your doctor if you have any side effects that bother you or do not go away. These are not all of the possible side effects of cyclizine. For more information, ask your doctor or pharmacist. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088..Visit Them
The pharmacokinetics of cyclizine in pregnant women
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Cyclizine is a histamine H1 receptor antagonist with anticholinergic and sedative properties. It is used to treat nausea, vomiting, and vertigo, and is available in over-the-counter and prescription formulations. Cyclizine crosses the blood-brain barrier and has been shown to be a safe and effective treatment for nausea and vomiting in pregnant women.
Cyclizine has a half-life of 3-6 hours in pregnant women and is rapidly metabolized by the liver. The mean elimination half-life is 9.5 hours. Cyclizine is not known to accumulate in tissues.
Cyclizine is rapidly and completely absorbed from the gastrointestinal tract, with peak plasma concentrations occurring within 1-2 hours of oral administration. Bioavailability is estimated to be 100%.
Cyclizine is extensively metabolized in the liver, with less than 1% of the parent drug excreted unchanged in the urine. The primary metabolites are hydroxylated derivatives of cyclizine.
Cyclizine is considered to be a safe and effective treatment for nausea and vomiting in pregnancy. There are no known contraindications to its use in pregnant women.
Cyclizine has been shown to be an effective treatment for nausea and vomiting in pregnant women. The most common side effects reported are drowsiness anddry mouth. Cyclizine is not known to accumulate in tissues and has a low potential for drug interactions. There are no known contraindications to its use in pregnant women.
We used pregnancysicknesssuport.org.uk to write this article about cyclizine when pregnant. Learn more.